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IUPAC name
Other names
3D model (JSmol)
Molar mass 274.448 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

3β-Androstenol, also known as 5α-androst-16-en-3β-ol, is a naturally occurring mammalian pheromone known to be present in humans and pigs.[1][2][3] It is thought to play a role in axillary odor.[3] It is produced from androstenone via the enzyme 3β-hydroxysteroid dehydrogenase.[1] Unlike its C3α epimer 3α-androstenol, 3β-androstenol shows no potentiation of the GABAA receptor or anticonvulsant activity.[4]

See also


  1. ^ a b Kanlayavattanakul M, Lourith N (2011). "Body malodours and their topical treatment agents". Int J Cosmet Sci. 33 (4): 298–311. doi:10.1111/j.1468-2494.2011.00649.x. PMID 21401651.
  2. ^ Richard L. Doty (27 January 2010). The Great Pheromone Myth. JHU Press. pp. 139–. ISBN 978-0-8018-9347-6.
  3. ^ a b Fischer J, Elsinghorst PW, Bücking M, Tholen E, Petersen B, Wüst M (2011). "Development of a candidate reference method for the simultaneous quantitation of the boar taint compounds androstenone, 3α-androstenol, 3β-androstenol, skatole, and indole in pig fat by means of stable isotope dilution analysis-headspace solid-phase microextraction-gas chromatography/mass spectrometry". Anal. Chem. 83 (17): 6785–91. doi:10.1021/ac201465q. PMID 21800819.
  4. ^ Sinclair PA, Hancock S, Gilmore WJ, Squires EJ (2005). "Metabolism of the 16-androstene steroids in primary cultured porcine hepatocytes". J. Steroid Biochem. Mol. Biol. 96 (1): 79–87. doi:10.1016/j.jsbmb.2005.01.030. PMID 15896952.