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20β-Dihydroprogesterone

20β-Dihydroprogesterone
20β-Dihydroprogesterone.svg
Names
IUPAC name
(8S,9S,10R,13S,14S,17S)-17-[(1R)-1-Hydroxyethyl]-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Other names
20β-DHP; 20β-Hydroxyprogesterone; 20β-OHP; 20β-Hydroxypregn-4-en-3-one; Pregn-4-en-20β-ol-3-one
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
Properties
C21H32O2
Molar mass 316.485 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

20β-Dihydroprogesterone (20β-DHP), also known as 20β-hydroxyprogesterone (20β-OHP), is an endogenous metabolite of progesterone which is formed by 20β-hydroxysteroid dehydrogenase.[1] It is a progestogen similarly to progesterone, with about one-fifth of the progestogenic activity of progesterone.[1]

See also

References

  1. ^ a b Bertram G. Katzung (30 November 2017). Basic and Clinical Pharmacology 14th Edition. McGraw-Hill Education. p. 728. ISBN 978-1-259-64116-9. In addition to progesterone, 20α- and 20β-hydroxyprogesterone (20α- and 20β-hydroxy-4-pregnene-3-one) also are found. These compounds have about one-fifth the progestational activity of progesterone in humans and other species.