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16α-Hydroxy-DHEA sulfate

16α-Hydroxy-DHEA sulfate
16α-Hydroxy-DHEA sulfate.svg
IUPAC name
[(3S,8R,9S,10R,13S,14S,16R)-16-Hydroxy-10,13-dimethyl-17-oxo-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-yl] hydrogen sulfate
Other names
16α-Hydroxy-17-oxoandrost-5-en-3β-yl sulfate; 16α-OH-DHEA-S
3D model (JSmol)
Molar mass 384.49 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

16α-Hydroxydehydroepiandrosterone sulfate (16α-OH-DHEA-S), also known as 16α-hydroxy-17-oxoandrost-5-en-3β-yl sulfate, is an endogenous, naturally occurring steroid and a metabolic intermediate in the production of estriol from dehydroepiandrosterone (DHEA) during pregnancy.[1][2] It is the C3β sulfate ester of 16α-hydroxy-DHEA.[3][4]

See also


  1. ^ Jerome F. Strauss, III; Robert L. Barbieri (13 September 2013). Yen and Jaffe's Reproductive Endocrinology. Elsevier Health Sciences. pp. 256–. ISBN 978-1-4557-2758-2.
  2. ^ Hiroshi Yamazaki (23 June 2014). Fifty Years of Cytochrome P450 Research. Springer. pp. 385–. ISBN 978-4-431-54992-5.
  3. ^ Mike S. Lee (8 May 2012). Mass Spectrometry Handbook. John Wiley & Sons. pp. 320–. ISBN 978-0-470-53673-5.
  4. ^ Shlomo Melmed; Kenneth S. Polonsky; P. Reed Larsen; Henry M. Kronenberg (30 November 2015). Williams Textbook of Endocrinology. Elsevier Health Sciences. pp. 839–. ISBN 978-0-323-29738-7.