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Clinical data
Routes of
Legal status
Legal status
CAS Number
PubChem CID
Chemical and physical data
Molar mass274.111 g/mol (freebase)
310.572 g/mol (HCl salt) g·mol−1
3D model (JSmol)

βk-2C-B (beta-keto 2C-B, bk-2C-B) is a psychedelic drug which is structurally related to 2C-B and BOB[1] and has been sold online as a designer drug.[2] It was found to be a polymorph and is prone to selfcondensation forming a dimer under basic to neutral conditions, similar to the reaction involved in pyrazine synthesis.[3]

Analogues and derivatives

Analogues and derivatives of 2C-B:


Substituted benzofurans:


Legal status


As of 12 October 2016, βk-2C-B became a controlled substance (Schedule III) in Canada.[4]


βk-2C-B is illegal in Switzerland,[5] Sweden[6] and the United Kingdom[7]

See also


  1. ^ Richard A. Glennon; Mikhail L. Bondarev; Nantaka Khorana; Richard Young; Jesse A. May; Mark R. Hellberg; Marsha A. McLaughlin; Najam A. Sharif (November 2004). "β-Oxygenated Analogues of the 5-HT2A Serotonin Receptor Agonist 1-(4-Bromo-2,5-dimethoxyphenyl)-2-aminopropane". Journal of Medicinal Chemistry. 47 (24): 6034–6041. doi:10.1021/jm040082s. PMID 15537358.
  2. ^ Giampietro Frison; Sara Odoardi; Samuela Frasson; Rocco Sciarrone; Giorgio Ortar; Francesco Saverio Romolo; Sabina Strano Rossi (July 2015). "Characterization of the designer drug bk-2C-B (2-amino-1-(bromo-dimethoxyphenyl)ethan-1-one) by gas chromatography/mass spectrometry without and with derivatization with 2,2,2-trichloroethyl chloroformate, liquid chromatography/high-resolution mass spectrometry, and nuclear magnetic resonance". Rapid Communications in Mass Spectrometry. 29 (13): 1196–1204. doi:10.1002/rcm.7211. PMID 26395784.
  3. ^ John D. Power; Pierce Kavanagh; John O'Brien; Michael Barry; Brendan Twamley; Brian Talbot; Geraldine Dowling; Simon D. Brandt (June 2015). "Test purchase, identification and synthesis of 2-amino-1-(4-bromo-2, 5-dimethoxyphenyl)ethan-1-one (bk-2C-B)". Drug Testing and Analysis. 7 (6): 512–518. doi:10.1002/dta.1699. PMID 25078895.
  4. ^ "Regulations Amending the Food and Drug Regulations (Part J — 2C-phenethylamines)". Controlled Substances Act. 2016-05-04.
  5. ^ "Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien" (in German). Der Bundesrat.
  6. ^ "Nya substanser klassas som narkotika eller hälsofarlig vara" (in Swedish). Folkhälsomyndigheten. 18 August 2015.
  7. ^ "Psychoactive Substances Act 2016". Home Office. Retrieved 8 September 2016.