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Gene Ontology Resource | The Gene Ontology (GO) project is a major bioinformatics initiative to develop a computational representation of our evolving knowledge of how genes encode biological functions at the molecular, cellular and tissue system levels.

Current release : GO terms | annotations
gene products | species (see statistics)

The Gene Ontology Resource

The mission of the GO Consortium is to develop a comprehensive, computational model of biological systems, ranging from the molecular to the organism level, across the multiplicity of species in the tree of life.

The Gene Ontology (GO) knowledgebase is the world’s largest source of information on the functions of genes. This knowledge is both human-readable and machine-readable, and is a foundation for computational analysis of large-scale molecular biology and genetics experiments in biomedical research.

GO Enrichment Analysis

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The network of biological classes describing the current best representation of the “universe” of biology. The molecular functions, cellular locations, and processes gene products may carry out.

  GO Ontology Overview   Browse in AmiGO   Download


Statements, based on specific, traceable scientific evidence, asserting that a specific gene product is a real exemplar of a particular GO class.

  GO Annotations Overview   View in AmiGO   Download


GO Causal Activity Model (GO-CAM) provides a structured framework to link standard GO annotations into a more complete model of a biological system.

  GO-CAM Overview   Browse GO-CAMs   Download

Tool & Guide

Tools to curate, browse, search, visualize and download both the ontology and annotations. Bioinformatic Guides (Notebooks) and simple API access to integrate GO into your research.

  GO Tools Overview   GO APIs Guide   GO GitHub