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AmiGO 2: Term Details for "cellular response to hypoxia" (GO:0071456)

AmiGO 2

cellular response to hypoxia

Term Information

Data health 
Accession
GO:0071456
Name
cellular response to hypoxia
Ontology
biological_process
Synonyms
cellular response to hypoxic stress, cellular response to lowered oxygen tension
Alternate IDs
None
Definition
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. Source: GOC:mah
Comment
Note that this term should not be confused with 'cellular response to anoxia ; GO:0071454'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%.
History
See term history for GO:0071456 at QuickGO
Subset
None
Related
Link to all genes and gene products annotated to cellular response to hypoxia.
Link to all direct and indirect annotations to cellular response to hypoxia.
Link to all direct and indirect annotations download (limited to first 10,000) for cellular response to hypoxia.

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Parents of cellular response to hypoxia (GO:0071456)
subjectrelationobjectcellular response to hypoxia  is_a  cellular response to decreased oxygen levels (GO:0036294) cellular response to hypoxia  is_a  response to hypoxia (GO:0001666) cellular response to hypoxia  is_a  cellular response to stress (GO:0033554)
Children of cellular response to hypoxia (GO:0071456)
subjectrelationobjecthypoxia-inducible factor-1alpha signaling pathway (GO:0097411)  BFO:0000050  cellular response to hypoxia positive regulation of cellular response to hypoxia (GO:1900039)  RO:0002213  cellular response to hypoxia regulation of transcription from RNA polymerase II promoter in response to hypoxia (GO:0061418)  BFO:0000050  cellular response to hypoxia regulation of cellular response to hypoxia (GO:1900037)  RO:0002211  cellular response to hypoxia positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia (GO:2000777)  BFO:0000050  cellular response to hypoxia intrinsic apoptotic signaling pathway in response to hypoxia (GO:1990144)  BFO:0000050  cellular response to hypoxia negative regulation of cellular response to hypoxia (GO:1900038)  RO:0002212  cellular response to hypoxia
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