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AmiGO 2: Term Details for "transmembrane signaling receptor activity" (GO:0004888)

AmiGO 2

transmembrane signaling receptor activity

Term Information

Data health 
Accession
GO:0004888
Name
transmembrane signaling receptor activity
Ontology
molecular_function
Synonyms
transmembrane signalling receptor activity, transmembrane receptor activity
Alternate IDs
GO:0004926, GO:0099600
Definition
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction. Source: Wikipedia:Transmembrane_receptor, GOC:go_curators
Comment
This term includes intracellular membrane receptors, e.g. IP3 triggered release of Ca2+ from intracellular stores.
History
See term history for GO:0004888 at QuickGO
Subset
None
Related
Link to all genes and gene products annotated to transmembrane signaling receptor activity.
Link to all direct and indirect annotations to transmembrane signaling receptor activity.
Link to all direct and indirect annotations download (limited to first 10,000) for transmembrane signaling receptor activity.

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Parents of transmembrane signaling receptor activity (GO:0004888)
subjectrelationobjecttransmembrane signaling receptor activity  is_a  signaling receptor activity (GO:0038023)
Children of transmembrane signaling receptor activity (GO:0004888)
subjectrelationobjectglycoprotein Ib-IX-V complex (GO:1990779)  RO:0002215  transmembrane signaling receptor activity purinergic receptor activity (GO:0035586)  is_a  transmembrane signaling receptor activity cytokinin receptor activity (GO:0009884)  is_a  transmembrane signaling receptor activity transmembrane receptor protein kinase activity (GO:0019199)  is_a  transmembrane signaling receptor activity ICAM-3 receptor activity (GO:0030369)  is_a  transmembrane signaling receptor activity opsonin receptor activity (GO:0001847)  is_a  transmembrane signaling receptor activity taste receptor activity (GO:0008527)  is_a  transmembrane signaling receptor activity MHC class II receptor activity (GO:0032395)  is_a  transmembrane signaling receptor activity MHC class I receptor activity (GO:0032393)  is_a  transmembrane signaling receptor activity G protein-coupled receptor activity (GO:0004930)  is_a  transmembrane signaling receptor activity serotonin receptor activity (GO:0099589)  is_a  transmembrane signaling receptor activity osmosensor activity (GO:0005034)  is_a  transmembrane signaling receptor activity non-tyrosine kinase fibroblast growth factor receptor activity (GO:0001571)  is_a  transmembrane signaling receptor activity nucleotide receptor activity (GO:0016502)  is_a  transmembrane signaling receptor activity neurotensin receptor activity, non-G protein-coupled (GO:0030379)  is_a  transmembrane signaling receptor activity GABA receptor activity (GO:0016917)  is_a  transmembrane signaling receptor activity MHC class Ib receptor activity (GO:0032394)  is_a  transmembrane signaling receptor activity Wnt-activated receptor activity (GO:0042813)  is_a  transmembrane signaling receptor activity semaphorin receptor activity (GO:0017154)  is_a  transmembrane signaling receptor activity latrotoxin receptor activity (GO:0016524)  is_a  transmembrane signaling receptor activity immunoglobulin receptor activity (GO:0019763)  is_a  transmembrane signaling receptor activity hedgehog receptor activity (GO:0008158)  is_a  transmembrane signaling receptor activity glutamate receptor activity (GO:0008066)  is_a  transmembrane signaling receptor activity transmembrane receptor protein phosphatase activity (GO:0019198)  is_a  transmembrane signaling receptor activity tiggrin receptor activity (GO:0005056)  is_a  transmembrane signaling receptor activity neuregulin receptor activity (GO:0038131)  is_a  transmembrane signaling receptor activity sulfonylurea receptor activity (GO:0008281)  is_a  transmembrane signaling receptor activity axon guidance receptor activity (GO:0008046)  is_a  transmembrane signaling receptor activity collagen receptor activity (GO:0038064)  is_a  transmembrane signaling receptor activity complement receptor activity (GO:0004875)  is_a  transmembrane signaling receptor activity netrin receptor activity (GO:0005042)  is_a  transmembrane signaling receptor activity apolipoprotein A-I receptor activity (GO:0034188)  is_a  transmembrane signaling receptor activity olfactory receptor activity (GO:0004984)  is_a  transmembrane signaling receptor activity death receptor activity (GO:0005035)  is_a  transmembrane signaling receptor activity acetylcholine receptor activity (GO:0015464)  is_a  transmembrane signaling receptor activity reelin receptor activity (GO:0038025)  is_a  transmembrane signaling receptor activity cytokine receptor activity (GO:0004896)  is_a  transmembrane signaling receptor activity
Reactome
R-HSA-193672